Introduction
Rosuvastatin is a prescription drug that is used to treat high cholesterol. It belongs to a class of drugs known as cholesterol-lowering drugs. This class of drugs is a combination of two drugs: Crestor (rosuvastatin) and Zocor (simvastatin). These drugs lower LDL cholesterol levels by inhibiting the enzyme that lipase.
By lowering LDL cholesterol levels, these drugs help to increase HDL levels, which can improve patient’s quality of life. Additionally, rosuvastatin and sildenafil can help improve blood flow to the penis, making it easier for men to get an erection and maintain an erection during sexual activity.
Mechanism of Action
Rosuvastatin and sildenafil are both liver-kidney-liver enzymes that break down cholesterol into smaller, smaller molecules that help lower blood sugar and lipid levels. When taken in amounts up to or exceeding 0.5 g daily, these drugs can reduce total and LDL cholesterol levels by up to 80% and 40%, respectively.
On the other hand, Crestor and Zocor are both liver-kidney-liver enzymes that break down dietary fat, and they are therefore able to increase the production of LDL particles in the liver by inhibiting the hepatic enzyme, HMG-CoA reductase.
Both Crestor and Zocor have demonstrated effectiveness in treating high cholesterol. However, with the exception of their mechanism of action, both these drugs are associated with side effects.
Effectiveness of Rosuvastatin
The effectiveness of either drug varies depending on individual factors such as kidney function, age, overall health, and lifestyle.
Common side effects of rosuvastatin include:
Rare side effects of sildenafil are more serious but less severe than those of rosuvastatin. These include vision changes, hearing loss, and prolonged erection (lasting more than 4 hours).
Common side effects of sildenafil are:
Some rare side effects of sildenafil are more severe than others.
Before you start taking these medications, it is important to consult with your doctor. They can evaluate your medical history, symptoms, and any other medications you may be taking before prescribing this medication. If you have any concerns about taking this medication, don’t hesitate to reach out for further queries.
In conclusion, both rosuvastatin and sildenafil are liver-kidney-liver enzymes that break down dietary fat, and their mechanism of action on cholesterol production are associated with side effects. It is important to seek medical advice before taking these drugs.
Conclusion
Rosuvastatin and sildenafil are both liver-kidney-liver enzymes that break down dietary fat, and their mechanism of action on cholesterol production are associated with side effects. However, with the exception of their mechanism of action, these drugs are associated with side effects. While both Crestor and Zocor have demonstrated effectiveness in treating high cholesterol, their mechanism of action on cholesterol production are associated with side effects.
Rosuvastatin (Crestor) and Zocor (Simvastatin)Rosuvastatin and sildenafil are both liver-kidney-liver enzymes that break down dietary fat, and their mechanism of action on cholesterol production are both associated with side effects. Rare side effects of sildenafil include vision changes, hearing loss, and prolonged erection (lasting more than 4 hours).
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Quick OverviewCrestor is a statin medication used to treat high cholesterol and low-density lipoprotein (LDL) cholesterol. It lowers your risk of a heart attack or stroke, reduce the risk of heart failure, and lower the risk of heart attacks and strokes in people with a family history of the indicated condition.Key BenefitsCrestor:a statin reduces the amount of cholesterol your body makes and provides additional weight loss benefits. Lowers the amount of plaque in your arteries, increases blood flow, and reduces the risk of heart disease and other complications. Crestor works by preventing the production of high levels of cholesterol and stopping them from making it through your blood. It is important to talk to your doctor about Crestor and to discuss other options with your doctor. In patients with a family history of this condition, Crestor may be prescribed when needed.
High Cholesterol
In addition to lowering cholesterol, Crestor helps lower LDL cholesterol by slowing the progression of atherosclerosis ( buildup of plaque in the arteries) and by making it more difficult for blood to flow to the heart. This leads to a decrease in heart attacks, strokes, and other cardiovascular complications.
How to Use
Crestor is generally taken orally once a day, with or without food, as directed by your doctor. Your dosage will depend on your doctor's instructions. In the absence of any health information the drug should be used to achieve a stable and even response to therapy. In most cases your doctor will guide you toward a dose that is gradually lowered based on your response. Some people using Crestor once a day are prescribed a dose that gradually reduces in duration.
Precautions
Do not use Crestor if you are pregnant or breastfeeding without consulting your doctor. Crestor has not been shown to cause harm to pregnant women or to cause harm to nursing infants. Crestor is not recommended for use in children under 6 years of age. Discuss with your doctor the history and the medicines you take before starting treatment with Crestor.
Storage
Store at a below 30°C temperature, away from light and moisture. Do not store in the bathroom. Keep Crestor out of the reach of children and away from pets. If you have any concerns about using this drug, consult your doctor or pharmacist.
Side effects
Some side effects may occur that may decrease your effectiveness of treatment. If any of these symptoms get worse or do not go away, please consult your doctor.
Get emergency medical help if you have an allergic reaction to Crestor or any other statin medication. Symptoms may include: skin rash, itching, hives, and difficulty breathing. If you have an allergic reaction, stop taking Crestor and call a doctor immediately. Other potential side effects of Crestor may include: muscle pain, weakness, dizziness, trouble sleeping. If you experience any of these symptoms, contact your doctor immediately. Common Crestor side effects may include: muscle pain, fever, joint pain, and muscle aches. Contact your doctor if your side effect worsens. Call your doctor immediately if you have an overdose of Crestor, or if you have any side effects that occur. Symptoms of overdose include severe dizziness, fainting, or coma. Call your doctor immediately if you have any unusual thoughts or feelings during treatment with Crestor.
Seek medical treatment right away if you have symptoms of infection (such as swelling, difficulty breathing) or serious side effects (such as: a skin rash, trouble breathing, chest pain, or changes in vision). In that case contact your doctor immediately.
Store at room temperature between 20°C to 30°C (30°C to 25°C) and protected from light. Keep Crestor out of the reach of children.
Consult your doctor before use if you are pregnant or breastfeeding.
Possible side effects
In the early morning hours of January 12, 2016, an article appeared inThe Washington Poston the sale of Lipitor and the loss of sales of the cholesterol medication Crestor.
A few weeks after the article appeared, thePostfound that thehad found no cases of patients receiving the drug. The post further noted that some patients taking the drug were taking Lipitor (atorvastatin), while others were taking the cholesterol-lowering drug statins (statins).
In an article posted online byThe Post, aNew York Timesarticle said, “the number of patients taking Lipitor increased from 18 in 2015 to 33 in 2016, the first year Lipitor was introduced.
“The number of patients taking Crestor has also increased from 16 to 34, while the number of patients taking Lipitor is increasing from 16 to 18.”
The Post also reported on the increasing use of the drug in patients with certain cardiovascular conditions, and noted that those with a history of heart attacks and strokes were also among those taking the drug.
“Lipitor has been available for years for those people with these conditions,” the post stated.
The Post said that as of January 2017, the U. S. Food and Drug Administration (FDA) had approved the use of the cholesterol drug Crestor (rosuvastatin).
Crestor, which was developed as an oral tablet, has been available since December of the same year by a different drug company. FDA approved rosuvastatin in the United States in June 2012, the same day the Post reported.
A similar drug is also being considered for generic competition. Generic rosuvastatin was approved in 1999. The manufacturer of the generic version of the drug, GlaxoSmithKline, had earlier this year in a lawsuit alleging that GlaxoSmithKline's marketing of the drug was anticompetitive and unlawful.
A generic version of rosuvastatin, called simvastatin, was approved in 2002 and is still available at the generic drug stores. It is also available for sale at Walmart and at Costco.
In 2012, FDA approved Crestor in the United States for the treatment of people with certain forms of benign prostatic hyperplasia and also for the treatment of other conditions such as male pattern baldness, benign thyroid gland enlargement, and an enlarged prostate.
As of Jan. 3, the FDA has approved Crestor for the treatment of people with benign prostatic hyperplasia and also for the treatment of other conditions.
In an FDA announcement, the FDA announced that it had reviewed the safety and efficacy of simvastatin and its combination with lopinavir/ritonavir in patients with the above conditions.
FDA said the company also said that it had conducted a review of the safety and efficacy of simvastatin and lopinavir/ritonavir in patients with certain types of benign prostatic hyperplasia, including and prostate cancer.
“The FDA’s review of the safety and efficacy of simvastatin and lopinavir/ritonavir is of no significance to the drug company,” said FDA.
The FDA has also approved the use of simvastatin and lopinavir/ritonavir in patients with certain types of benign prostatic hyperplasia and also for the treatment of other conditions.
In a news release, the FDA said, “We have determined that simvastatin and lopinavir/ritonavir have no effect in patients with the above conditions.”
According to a person familiar with the FDA’s announcement, the company’s regulatory review is the first time that a company has approved a new drug for treating a disease.
The FDA, however, does not appear to approve the drug for treating conditions such as:The FDA said it had not approved any of the drugs for the following conditions.
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Crestor is used to treat hyperlipidemia (increased blood cholesterol levels) in adults. Crestor is also used in children and adolescents.
Crestor contains the active ingredient rosuvastatin, which is a lipase inhibitor that prevents the conversion of cholesterol to an LDL-cholesterol. Crestor is used for the treatment of (high cholesterol) and (hypercholesterolemia).
Crestor works by blocking the action of cholesterol in the liver. Inhibition of cholesterol is the main cause of high cholesterol levels. It reduces the production of bad cholesterol by the liver.
Crestor contains both the active ingredient rosuvastatin and the inactive ingredients calcium carbonate, magnesium stearate, hypromellose, hypromellose, titanium dioxide (E171), yellow ferric oxide, and iron oxide red. The main ingredients are:
Each tablet contains 50 mg of rosuvastatin and 50 mg of calcium carbonate.
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